Multi-platinum recording artists Barenaked Ladies celebrate over two decades of hits with a career-spanning retrospective that includes the group's biggest singles and, for the first time on CD, their beloved theme to the television series Big Bang Theory. Sequenced in chronological order, the album kicks off with 'If I Had $1000000' from the group's 1992 major-label debut, Gordon, and much of which draws on the critical and commercial success the Barenaked Ladies enjoyed with Stunt (1998) and Maroon (2000).

Hits From Yesterday And The Day Before also features tracks from the band's recent independent releases, including 'Easy' from 2006's Barenaked Ladies Are Me, 'You Run Away' from last year's All In Good Time, and the aforementioned 'Big Bang Theory Theme,' from the hit television series, which recently went into syndication.